http://www.novonordisk-jobs.com/feeds/cell-culture-jobs/ Custom RSS Feed for cell-culture-jobs Sun, 19 May 2013 19:22:02 GMT en-us /sites/novonordisk/images/Novo_Banner.gif http://www.novonordisk-jobs.com/feeds/cell-culture-jobs/ 720 Title Sr. Research Associate (Type 1 Diabetes)
Job Category Research & Development
Job Description PURPOSE:
The role of Research Associate will provide research-based competencies in support of the T1D Research and Development Center aimed at accelerating the path of antigen-specific and biological therapies for autoimmune diabetes. This position will be responsible for providing peer leadership and technical support in the laboratory for research experiments and data integrity.

RELATIONSHIPS:
Reports to a Research Scientist in T1D. Internal relationships include research associates, scientists, project teams both locally and globally.

ESSENTIAL FUNCTIONS:
• Collect data from human experiments relevant to T1D, work with supervisor to perform basic data analyses and provide guidance to Research Associates.
• Perform proper record keeping to ensure data integrity of NNRC. Show evidence of increasing ability to correctly interpret data.
• Increasing ability to design and perform human biomarker studies in close collaboration with the Research Scientist. Conduct in-vitro analyses of immune cell phenotype and function, using FACS, ELISPOT, T cell assays, Treg analysis and other in-vitro assays. Independent assay development required.
• Handle and process human blood samples to isolate immune cells.
• Order lab supplies as needed and perform other job-related duties as assigned.

PHYSICAL REQUIREMENTS:
Works with human and animal blood and tissue; works in a laboratory environment that may include hazardous chemicals and blood borne pathogens. May require 5% travel.

KEY SUCCESS FACTORS: EDUCATION, EXPERIENCE, KNOWLEDGE AND SKILLS
• BS with 2-4 years relevant experience.
• Good understanding of immunology and immunological assays, including but not limited to ELISpot, immune cell functional assays, ELISA/Luminex, and histological analyses.
• Experience with multi-parameter flow cytometry required.
• Experience working with human and animal blood, tissues and/or cells as well as proper handling of biohazard material.
• Ability to work independently and develop assays.
• Strong technical skills, including cell culture sterile technique required.
• Experience working in BSL2 conditions and animal models preferred.
• Exercises judgment within defined procedures and practices.
• Computer proficiency, database management and the ability to learn new software programs.
• Excellent skills in collecting data and accurately maintaining laboratory notebooks.
Department NN DIABETES CENTER - SEATTLE (1)
Position Location US - Seattle, WA
City Seattle
State/Provinces US - WA
Degree Required Bachelor's Degree Required
Percent Travel 0 - 10%]]>Sun, 12 May 2013 02:59:00 GMThttp://www.novonordisk-jobs.com/job/Seattle-Sr_-Research-Associate-%28Type-1-Diabetes%29-Job-WA-98101/2442877/?utm_source=J2WRSS&utm_medium=rss&utm_campaign=J2W%5FRSShttp://www.novonordisk-jobs.com/job/Seattle-Sr_-Research-Associate-%28Type-1-Diabetes%29-Job-WA-98101/2442877/?utm_source=J2WRSS&utm_medium=rss&utm_campaign=J2W%5FRSS Title Research Associate (Type I Diabetes)
Job Category Research & Development
Job Description Purpose:
The role of Research Associate will provide research-based competencies in support of the T1D Research and Development Center aimed at accelerating the path of antigen-specific and biological therapies for autoimmune diabetes. This position will be responsible for providing technical support in the laboratory for research experiments and data integrity.

Relationships:
Reports to a Research Scientist in T1D. Internal relationships include research associates, scientists, project teams both locally and globally.

Essential Functions:
• Collect data from mouse and human experiments relevant to T1D, work with supervisor to perform basic data analyses
• Work with supervisor to perform proper record keeping to ensure data integrity of NNRC
• Assist in the design of and perform human and mouse biomarker studies in close collaboration with the Research Scientist. Conduct in-vitro analyses of immune cell phenotype and function, using FACS, ELISPOT, T cell assays, Treg analysis and other in-vitro assays. Some assay development required.
• Perform in vivo and ex vivo experiments, in collaboration with colleagues, to evaluate therapies for treatment of T1D in mice. Some assay development required.
• Handle and process human blood samples to isolate immune cells
• Order lab supplies as needed and perform other job-related duties as assigned

Physical Requirements:
Works with human and animal blood and tissue; works in a laboratory environment that may include hazardous chemicals and blood borne pathogens. May require 5% travel.

Key Success Factors (Education, Experience, Knowledge and Skills):
• BS with minimum 1 year relevant experience.
• Basic understanding of immunology and immunological assays, including but not limited to multi-parameter flow cytometry, ELISpot, immune cell functional assays, ELISA/Luminex, and histological analyses.
• Experience working with human and animal blood, tissues and/or cells as well as proper handling of biohazard material
• Ability to work independently and support assay development required
• Strong technical skills, including cell culture sterile technique required
• Experience working in BSL2 conditions and animal models preferred
• Computer proficiency, database management and the ability to learn new software programs
• Excellent skills in collecting data and accurately maintaining laboratory notebooks
Department NN DIABETES CENTER - SEATTLE (1)
Position Location US - Seattle, WA
City Seattle
State/Provinces US - WA
Degree Required Bachelor's Degree Required
Percent Travel 0 - 10%]]>Mon, 06 May 2013 00:00:00 GMThttp://www.novonordisk-jobs.com/job/Seattle-Research-Associate-%28Type-I-Diabetes%29-Job-WA-98101/2583568/?utm_source=J2WRSS&utm_medium=rss&utm_campaign=J2W%5FRSShttp://www.novonordisk-jobs.com/job/Seattle-Research-Associate-%28Type-I-Diabetes%29-Job-WA-98101/2583568/?utm_source=J2WRSS&utm_medium=rss&utm_campaign=J2W%5FRSS
- Research & Development
- Denmark - Hillerød

Are you passionate about early applied development within cell replacement therapy? Are you ready to drive the development of a stem cell based therapy ultimately to get one step closer to finding a cure for diabetes and its complications? Then join CMC Stem Cell Development at Novo Nordisk A/S, Denmark. Our objective is to develop cell replacement therapy into a viable option for treating Diabetes Mellitus by developing procedures for pilot scale cultivation and purification of beta cells derived from stem cells.

About the department
In the initial phase you will contribute to the building of a strong new department in CMC and assist in clarifying the need for technical process setup.

You will be part of CMC API Development in an organization with approximately 350 employees in Novo Nordisk Research and Development.

The job
The objective is to lead innovation within the area of bioprocess development that focuses on the translation of stem cell research into clinical application. As part of the development team, you plan, execute and evaluate the experimental work towards establishing a robust procedure for the manufacture of beta cells to be used for clinical trials.

Currently, robust and scalable procedures for the manufacture of beta cells derived from embryonic stem cells do not exist. However, along with the team, you will ensure that the project delivers according to the specifications and deadlines. In all your work, you promote scientific excellence and contribute to the positive, enthusiastic working environment.

Qualifications
You have a strong background in human embryonic stem cells, molecular biology or developmental biology. We are particularly interested in applicants with previous experience within development of processes to be used for manufacture of drug substances for clinical trials. Hence, experience with GMP will be an advantage.

As a person you are proactive, outgoing and possess a strong desire to get the job done. Your creative mindset and positive outlook on your work enables you to get to the bottom of challenges and provide new methods and perspectives. At the same time, you have a well-structured approach to your work, leaving no stone unturned. You are a team player and comfortable working in a dynamic work environment. You have a relevant academic background (minimum PhD) and you are able to communicate scientific matters to colleagues and external stakeholders fluently in English.

In Novo Nordisk is your skills, your commitment and your ambitions, which helps us to improve many people's lives. In return we offer you the opportunity to work with exceptionally talented colleagues, and we offer you a wide range of opportunities for professional and personal development.

Contact
For further information, please contact Sanne Bové at +45 3075 5635 or Arne Staby at +45 3075 9989.

Deadline
17 May 2013.]]>Sat, 18 May 2013 05:31:00 GMThttp://www.novonordisk-jobs.com/job/Hiller%C3%B8d%2C-Denmark-Chemist/2557336/?utm_source=J2WRSS&utm_medium=rss&utm_campaign=J2W%5FRSShttp://www.novonordisk-jobs.com/job/Hiller%C3%B8d%2C-Denmark-Chemist/2557336/?utm_source=J2WRSS&utm_medium=rss&utm_campaign=J2W%5FRSS Title Research Associate (Cellular Immunology)
Job Category Research & Development
Job Description Provide technical support to the Cellular Immunology team within the Novo Nordisk Research Center. Provide excellent experimental skills in the analysis of different types of immune cells in cell-based assays to support development of biological therapeutics in autoimmune & inflammatory diseases. Incumbents have responsibility for research experiments and data integrity, as assigned by management. Incumbents must be able to design and implement an experiment based on an overall description of the intended outcome.

Relationships:
Reports to the Department Head. Internal relationships include on-site research scientists.

Essential Functions:
Achieve business goals, share learnings, knowledge and skills and promote cross-functional teamwork.
Complete assignments requiring a good knowledge of techniques and practices related to the research area.
Ensure data integrity of NNIRC. Conduct data collection, interpretation and ensure proper documentation of experimental data. Maintain laboratory notebooks.
Identify the correct methods and perform manual calculations for sample preparation.
In close collaboration with the research scientist, design and perform laboratory research experiments.
Manage site inventory. Order laboratory supplies and equipment. Maintain the laboratories and perform other job related duties as assigned.
Perform in vitro research to support multiple drug discovery efforts.
Provide responsible and skilled technical assistance in support of the research projects.

Additional requirements:
Approximately 5% overnight travel
Ability to work flexible hours and overtime

Key success factors (Education, Experience, Knowledge and Skills):
BS with 2 years of relevant experience from basic research or the pharmaceutical industry required. Qualified incumbents could also be entry level MS graduates.
Computer proficiency and the ability/interest to learn new software programs required.
Excellent skills in collecting data and accurately maintaining laboratory notebooks required.
Experience working with human and animal (mouse) blood, tissues and/or cells as well as proper handling of biohazard material required.
Good understanding of immunology and immunological assays, including but not limited to ELISpot, immune cell functional assays, and ELISA/Luminex required.
Experience with multi-parameter flow cytometry required.
Flexibility and the ability to work in a fast-paced, team-oriented environment.
Strong technical skills.

Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time. Additionally, this job description reflects management’s assignment of essential functions. It does not prescribe or restrict the tasks that may be assigned.
Department NNRC - CELLULAR IMMUNOLOGY
Position Location US - Seattle, WA
City Seattle
State/Provinces US - WA
Degree Required Bachelor's Degree Required
Percent Travel 0 - 10%]]>Tue, 23 Apr 2013 00:00:00 GMThttp://www.novonordisk-jobs.com/job/Seattle-Research-Associate-%28Cellular-Immunology%29-Job-WA-98101/2562654/?utm_source=J2WRSS&utm_medium=rss&utm_campaign=J2W%5FRSShttp://www.novonordisk-jobs.com/job/Seattle-Research-Associate-%28Cellular-Immunology%29-Job-WA-98101/2562654/?utm_source=J2WRSS&utm_medium=rss&utm_campaign=J2W%5FRSS
- Production
- Denmark - Hillerød

Would you like to work with production processes and ensuring quality? Then you might be our new chemist. We are searching for a chemist to support fermentation in our API production in Hillerød.

About the department
Biopharm API Mammalian Cell Production is placed in Hillerød where we are 100 colleagues. We produce Haemophilia API and the department have responsibility for product quality until delivery to our filling plant. The production process consists of cultivation of mammalian cells and a recovery process based on liquid chromatography. We are on the point of manufacturing to market. You will play a key part in helping people with Haemophilia all over the world.

The Job
In close cooperation with your colleagues in the production support team you will ensure that the cell growth process is in compliance with all regulations. As such, you will make sure that we follow up on the products and handle the documentation according to the GMP standards before releasing a product. You will spend time on the shop-floor, knowing that being close to the process and the operators will help you solving problems early and effectively. On an on-going basis, you will handle systematic problem solving and trouble shooting on deviations. Additionally, you will optimise processes in close collaboration with other support functions and the QA-functions. Depending on your skills and experience you will be involved in one or more of the parallel projects running in the department. As you will be part of production support team you will be expected from time to time to support production on problem solving also outside normal working hours. You can expect a dynamic and varied working day with an informal atmosphere.

Qualifications
You hold a degree in Engineering, Pharmacy or another discipline of the natural sciences. This is supplemented with a couple of years’ relevant experience within pharmaceutical production and preferably within cell growth. You have a strong mind-set for quality and compliance and preferable LEAN experience. As a person you can stay focused in a busy working day and you always approach tasks and colleagues with a positive attitude and energy. You are analytical and work in a structural way and are used to deliver according to deadlines. You possess good communication skills both in Danish and English.

At Novo Nordisk, your skills, dedication and ambition help us to change lives for the better. In exchange, we offer you an opportunity to work with extraordinary talent and benefit from a range of possibilities for professional and personal development.

Contact
For further information, please call Karen Mette Krieger Lassen on+ 45 3075 3598.

Deadline
26 May 2013.]]>Sat, 11 May 2013 00:00:00 GMThttp://www.novonordisk-jobs.com/job/Hiller%C3%B8d%2C-Denmark-Chemist/2593399/?utm_source=J2WRSS&utm_medium=rss&utm_campaign=J2W%5FRSShttp://www.novonordisk-jobs.com/job/Hiller%C3%B8d%2C-Denmark-Chemist/2593399/?utm_source=J2WRSS&utm_medium=rss&utm_campaign=J2W%5FRSS Title Sr. Research Scientist- Translational Research, Cellular Immunology
Job Category Research & Development
Job Description PURPOSE:
The Cellular Immunology department is engaged in identifying, evaluating, and validating potential protein-based lead candidates and protein-drug targets in the area of autoimmune and inflammatory diseases. The incumbent will provide leadership for NNRC’s pre-clinical translational immunology research activities, developing and executing plans for ex vivo target engagement, occupancy and biomarker assays as well as mechanism of action studies with human patient material. The candidate will bring specific expertise in the underlying pathological processes of autoimmune diseases and will come with a track record of successfully enabling the transition of therapeutic candidates into clinical development through translational research activities. The incumbent will collaborate with external partners as well as across NN departments and research sites.

RELATIONSHIPS:
Reports to the Director, Cellular Immunology at Novo Nordisk Inflammation Research Center (NNRC). Supervise the work of at least one Research Associate

ESSENTIAL FUNCTIONS:

SCIENTIFIC ROLE:
• Work within project teams to develop dose guiding and target engagement biomarker strategies.
• Design, develop, and execute studies with patient samples for mechanism of action and biomarker assessment.
• Provide insights into clinical aspects of disease.
• Use translational research expertise to advise projects on relevant patient populations and therapeutic differentiation strategies
• Recommend research directions and implement technologies for the department’s activities, which include functional cell-based immunological assays and approaches for discovering and validating targets.
• Actively review patents and patent applications in areas of research relevance and identify opportunities.
• Assume responsibility for project design and implementation.
• Communicate regularly with international colleagues within Novo Nordisk.
• Day to day supervision of research personnel in Cellular Immunology.
• Develop and manage relevant research protocols in support of pre-clinical translational research efforts
• Draft scientific reports and prepare presentation slides.
• Implement and supervise laboratory studies in support of autoimmunity and inflammation research.
• Interpret and properly document experimental data.
• Maintain current awareness of scientific literature in core disease areas.
• Provide a safe and functional research environment.
• Provide unified research-driven innovation and continuous improvement within own Department and across Departments.
• Work with Director to define and implement therapy area-focused research strategies consistent with organizational goals.

MEDICAL AND RESEARCH COMMUNITY LIAISON:
• Ensure scientific representation at external scientific meetings and conferences.
• Expand existing external research network.
• In compliance with the research strategy and in collaboration with the project teams, identify and expand external research contacts.
• Publicize internally meeting results and collaborative opportunities.
• Write, review and approve collaborative research manuscripts.

SCIENTIFIC SUPPORT FOR OTHER COMPANY ACTIVITIES:
• Oversee company interactions with the expert community (i.e. Advisory Boards, scientific meetings, etc.).
• Provide development opportunities at other company sites.
• Provide internal education and ongoing scientific support as needed.

PHYSICAL REQUIREMENTS:
• Approximately 20% overnight travel

KEY SUCCESS FACTORS: EDUCATION, EXPERIENCE, KNOWLEDGE AND SKILLS
• A PhD, M.D. / PhD, or equivalent with minimum 7 years relevant industry required.
• Prior research or related experience in autoimmunity and inflammation.
• Excellent written and oral communication skills required.
• Excellent interpersonal and motivational skills.
• Extensive experience in pre-clinical translational research in Autoimmunity/Inflammation with a focus on use of patient samples, development of ex vivo assays.
• Experience in the supervision and training of technical staff highly preferred.
• Flexibility and the ability to work in a fast-paced, team-oriented environment are required.
• Industry experience with protein-based biologics or small molecules
• Proven innovative skills.
• Knowledge of the biopharmaceutical development process.
• Strong cellular immunology training and background.
• Strong experience and background in autoimmune diseases and Inflammation.
Department NNRC - CELLULAR IMMUNOLOGY
Position Location US - Seattle, WA
City Seattle
State/Provinces US - WA
Degree Required Doctorate Degree Required
Percent Travel 10 - 20%]]>Tue, 23 Apr 2013 03:00:00 GMThttp://www.novonordisk-jobs.com/job/Seattle-Sr_-Research-Scientist-Translational-Research%2C-Cellular-Immunology-Job-WA-98101/2504894/?utm_source=J2WRSS&utm_medium=rss&utm_campaign=J2W%5FRSShttp://www.novonordisk-jobs.com/job/Seattle-Sr_-Research-Scientist-Translational-Research%2C-Cellular-Immunology-Job-WA-98101/2504894/?utm_source=J2WRSS&utm_medium=rss&utm_campaign=J2W%5FRSS